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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332ce0e53c4325b76399fbd27d0f1ec5406d4106ed8cda4f60ddbd4f1e884431' 
  AND token = 'yJzUIFTdtEwp1r/2PiYggblMcQCKlcUtEqAQo2g3GWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}