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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180d674a263b89d321c86b05ec6c6941739ddd5e6e8efccc8a887d24da13eed4' 
  AND token = 'BkI6s/uNXFQOC53Ko8TDOQKZU9isnw9xnh2xp2o2sWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}