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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9253a8995111a431940caa042927834e44163ddcb1232391c33e266571e6b80c' 
  AND token = 'fjNvvUwuG05wUQ+/nMhC2vMske88nveb1xMlzyTCduI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}