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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72e9f648a7d365b37e0a376f66299de7a15e6f9bb559f9701c149083ac44509' 
  AND token = 'Jnzi22AVg/5Dq0cOrbd24/JbjackDAVDjtMR/nSiVrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}