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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5775108986f405d5c7b6c9533fb00c1d5e9d4fe6374785819da6fb91f6ec316' 
  AND token = 'UgPbtwdctg0rceufOV8YRwwulN60wAtqim/7jc46KLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}