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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb44d53a099ce55923449ef41626e5afe36ba89c9cbdf2a397f87c67a6f55a20' 
  AND token = 'v+1dtoFYMVgq7bdk/AoRMTIdkz4Dy2XntOagXmvHvrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}