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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07d54a0c4c1bf022cb759376947db3e09c627c1426721b307d1154b95a668a71' 
  AND token = 'II1AqRO356RLLzCLa3RK9Frd8GM8NcZ2Hu2xSJtNLec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}