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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d9bbbc71284a78bbfee8e80ca4e70c76a45e19e78993c5f219d0e34be91197' 
  AND token = 'eeLEHWmXRC0JIwDXnNqK0fkiws10eGltFNzUYPO8vqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}