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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9dbb7ade4f2c66396e4752ee83b58e957393be11edfc6f1a9efb9500e1e256' 
  AND token = 'm4b0MMF4TWr1d4xqFsQMxCvN2umsfhynQjuIhyuwdmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}