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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43586d97c069f266d1667553d02838f394dfa9be986cadc70ca86e17f20e951' 
  AND token = 'oWEMdDoEhOOOnsdaMekFrjpAaxsn825bM7BuTbtNo/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}