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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1186e16abe0b747ad353a1facea2fcb4534d9e729198f66d47a6171644df494' 
  AND token = '/WLYQonswVDqTYkJ+DtfOQfOlfTdiI1KREmgq7JN3Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}