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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c27c18a76e606c767f0428abe8a5957b807f70c5c464ee3e2ce1490f9ee8681' 
  AND token = 'MX9yX0Mt1aXCxYZuO2zr/7azprwMR+pTDyTR/SmikqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}