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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8c02b641d8eec8653d1fec226cbd97f316e7ee4a9d5730a6427b6371b8920f' 
  AND token = 'p/VA+p2sF8kY0XZcnJf1SrYwu5EPSrDA8GXlT8oIQjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}