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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b016dd2bd4fd7db06b1dfab458a8532e87583264a2d6c4e1906d3efadd4b03c' 
  AND token = 'Ldq1UpkU6dunASPJwzCknlHYcjT8MaE0Wz69PnkR6rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}