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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03593a3cb8a2786ef971828937aee188800485076266f04e105312a38f579d66' 
  AND token = 'Heit+D9pNFgK1qPTfQfc3F3w+Qyl9zvYD2wzibHvqVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}