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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335c8f2dfb218f56d25dc2fe0c23d15b1791020309dcb111c744583117b1dbd3' 
  AND token = '1uj1UvdWJKEY9qp2fsEdeniwHvxaRBZVqnelOoCwLIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}