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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3c228a0b7e7b6c75e449ee9faf38d853446bac4fde018ffed96853d4336e4c' 
  AND token = 'bP2uIiKyYC+J5wc13WW7vEJJnkvvtTOXq9ItwjfmAjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}