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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ef96db322b39eda0f95a38ad68cc5e6f30ffc26b2a1d889f449d311195283d' 
  AND token = '8s9Ibqos/mHxeUUws2yrkH91rAi+chb8brNa7MtYwnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}