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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2045adf61cd878acfb9d9930d6ba0d4213c8326bc2d2a9c22328c6b933928004' 
  AND token = 'eCDUgoFMlOEzb30IQ1Y+BjGkyYAJFxFD3HaX506n46w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}