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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de41c4ae4996920b4a47039d13fdd9004be967d1a80d569fda91c4cb06a1e2bc' 
  AND token = 'MABvKTWbicEJR3TB2lP1IT7I73fefFQaYojnnJX+3Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}