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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5293b73b9cff08852e40ebefdd34647aa83c049d49a53d4c20ee0d5ca71ddb' 
  AND token = '0vy26wjsAVzvTRDLtCI7EOUIEIgGqGMJSIzOZ1s7GEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}