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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f406a3a13e3cf795a0ee1754d51bf3a463d1b0341a9efc26d9d0f32078f86b' 
  AND token = 'MUqSua+JMeeY25UZPzvbUCSxNoqLWm2iJt0MTZXQ3YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}