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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c042e74c01074a95df5a5609e6a43a71c1847709490de527e34e75c5ce289a1' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}