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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f21428226de88dd0367d2206807bc7d726ed12add38e9735d9a448809737ce' 
  AND token = 'cL4g1EV1CWs1+Mzq6ZYILkmKVD9GqFPEt3MOwa8Q75E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}