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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d2e1669f41a6e1cb05f68ea0bdf53cfd199d3f0a95d4e44cddaf77371600b3' 
  AND token = 'nOOl/Uz6OuR6tHuEx9TaqlfPl2n6wKZdQWBd6SMmlOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}