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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb661e0025ac6615aac15642552cb00f1bf647e105e0484078f0c36c5272fe2' 
  AND token = 'ifFbd+4glWM1T6f3FigKrN2Bt6BFk85fYT5vJUE7mNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}