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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259de530d0ce76d42c156d7fdeb0628dff2286be8ff77c99e01e6200fb858075' 
  AND token = 'bct0SW2kiteGg4zR87m2xc0aY7vOCaE2PB3uUVrBy/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}