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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a351729281bde5f1b1921d1ef08b6e70d93a2df41189252df65cab86a2df5549' 
  AND token = 'iEdLBZwSjH1JxSZPCCdPru6j6aKPlG41Y7yHYQ1NE/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}