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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447ec22f6c9f11d1998c8ac2c1533c5dedcd47bbc92dbb9087dbb33eedac6073' 
  AND token = 'lJ7fN9aRk+XL45/Gl3fEN4OlWyFN2qSMtJJTu+3cM2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}