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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369de0c7feaf524546a3c455b0471f1530e6c15dc06ad14615fe0f12a9d1fa3f' 
  AND token = 'ZeJCqMzgkrKgudhbgM0+UVYjAlCOpdSmU0r33wxHdPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}