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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d27ad1c8ca3118ec07c2f9e0e7f66c741381fdb64228af486aa8fffd634f2a1' 
  AND token = 'bUyEmLwA2N4qC7LUUNaM5GulzOgAaPZKfFTqhXtHA+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}