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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed65c2bde31d7bafeb8c4534949b71cef660c487d78bc4219986a8fdab7e5501' 
  AND token = 'IIvSjxo0ls+tcftIV2kp9ZJh5Tjde16iZHYOzchJ6ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}