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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185b0f828febcf5607f726e5dfb29ee9b7a5d2c1b4ee6b7dfc7f4f1c86a26ac3' 
  AND token = '22Ma9SAoLAnSCBsSrXe2BUDQ91KQhrEm3R7PkiowpdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}