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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c571d6e7db63a0898c233b39ce3774b69b9ea183823491b841df3fa4a59081' 
  AND token = 'x1VShnZkGYMdYdqhtQ8YnhSABaPbdT+Gcq9mlTSviE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}