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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7206be55354ce3e27de9eecddf8a50ee59d79c25cb0872233c34556e80f5a0f2' 
  AND token = 'RoRfHkeKleweFVYGhcMx/DvoCZvGCHnYVkOC+m/0TpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}