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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fa8622f40d5bb2a070b64350efffb84ee680448e3a50512bde277a07c1452ad' 
  AND token = '0x6HUmc6aTgyMYe67At26sHGWu+dW+5jnkeWX6odFIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}