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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6c35e8a3bff6bc65c4350d3774b610f47a76ef81e172d7a22c72675626659d' 
  AND token = '9umA1arqKfKPEplFkJxARdAqS7b+a1WW/z/LM3p+VSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}