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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16189da52f3342bb5eb1371381f9089e09b8a439060b162df0ed5d577372a8fb' 
  AND token = 'nRxomaW8RfK7vbMeY1AQNvJ5mH4na0xICuZGDMsGGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}