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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce1a19709fb421690ce2e85843df3ca3f621e693e3f8d27eba250c4d47b295f' 
  AND token = 'wfktjmCO+zyu75Wj7EQCjjl3jN9Tar/N/9fmQFIEiGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}