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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73c74dae28f4f493eb9b50b3dc2bdd433ab0a80ca14ba652d84724160bd55500' 
  AND token = 'OWSD+bx6dV7kYNTnl9GE1G7YyEerPb8/K6FqdXRwaCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}