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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edf29a3c0ed4510220dc4d5817aee558a81517fd09107d2d47b5117d623b06cf' 
  AND token = 'Ff2kHDST/HzQhnWL1lhPLmefjpaUhC8syTaakcT9fUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}