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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfbff736dce78abd86592559c85c5e22acf348c59a2d0eac8563edc0d4d487da' 
  AND token = 'sSKB2B6X8BL7+TSIYQxRJZt4aSARCFhZU4kgLwzg+fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}