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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3411e39d901cfc53b0bc1fedef0d03fedd336310d2dc1f17cc7a2a6821e771fe' 
  AND token = 'DxIJbt+DREub7rPJ+muVKVvc1Giby/9hXkL0KYtQw9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}