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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca8e7be30f4d48f8adbadb578a0d5b5cb68b44b3adf630509e915a744f3259d5' 
  AND token = '++wd4q5xNSZ0bjlul+epNTJAmM/93ogQFska2WD30mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}