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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ee6bf39ce7a5bb4eb39d09f7158f62043efcac8c4162e10860f13205d0894c2' 
  AND token = 'VLIRQBWpoJhOIcICwxc7MTwQoExRIVmKWyADGtt4Y8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}