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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b89e4d0a05bcb241c0df49da92662a68f668c53f0ebda559f4b384bebb5e04' 
  AND token = 'zkMlKLpT4/g25ly6OD7gq9ShI9bVhJDCrbzRE/WMMfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}