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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7122862cefc248eaf296eeda9036ba18ba63d47906e0b6ca3c1ea310c422abae' 
  AND token = 'jYFMDrdfPthSvr+6ghGggfqSU8atRrGXaj0pA/BOgeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}