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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d107a016ed94264fe217a50ec6dc2c7779b7609d1d9ad05ee448c09591b866' 
  AND token = 'gvqxjPZ3buNqr5G1UIno2ymb8ZVuIk94Z9VBpyAsEAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}