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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8364b390f9b9c8684fb568e8666ace4af64768d38d9e1541882db3fea49b8eb' 
  AND token = 'aHlB5x7/VlzN/eOtSoxQkeiEpPD3sUP81IDfxcIbN5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}