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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d5a5542738e120d19fa77bec53d7ab444a21020333017d4fefeeb0ab1c47da5' 
  AND token = 'owVtfPLawb1DA51huWkx1lW8JTfpmMd8t09su3+ODcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}